Standard Article

Hazardous Agents


  1. Wolfgang Urfer

Published Online: 15 SEP 2006

DOI: 10.1002/9780470057339.vah005

Encyclopedia of Environmetrics

Encyclopedia of Environmetrics

How to Cite

Urfer, W. 2006. Hazardous Agents. Encyclopedia of Environmetrics. 3.

Author Information

  1. University of Dortmund, Germany

Publication History

  1. Published Online: 15 SEP 2006


Evaluation of hazards associated with exposure to chemicals, understanding of relationships between dose and adverse effect, extrapolation of effects from high experimental doses to low doses associated with actual exposures, and extrapolation from effects observed in animals to effects expected in humans are the main issues of statistical research in risk assessment of hazardous agents. Statistical aspects of inhalation toxicology, proof of hazard, genetic toxicology and the role of oncogenes in carcinogenesis are discussed. Finally, the need for more statistical research to identify hazardous agents by DNA and protein sequence analysis is outlined.