Standard Article

Multiple Endpoints

General

  1. Stuart J. Pocock

Published Online: 15 SEP 2006

DOI: 10.1002/9780470057339.vam043

Encyclopedia of Environmetrics

Encyclopedia of Environmetrics

How to Cite

Pocock, S. J. 2006. Multiple Endpoints. Encyclopedia of Environmetrics. 4.

Author Information

  1. London School of Hygiene and Tropical Medicine, Uk

Publication History

  1. Published Online: 15 SEP 2006

Abstract

In any experimental or epidemiologic study, there may be several disease or response outcome measures that one wishes to relate to markers of environmental exposure and/or other relevant risk factors. Such multiple endpoints may well be justified scientifically since one often cannot anticipate exactly which measure of response will be affected by exposure. The statistical problem is that one then runs the risk of data dredging and distortive reporting with a post hoc emphasis on the most statistically impressive findings.