Standard Article

Teratogenesis, Environmental

Environmental Health

  1. Brent A. Coull1,
  2. Lewis B. Holmes2

Published Online: 15 SEP 2006

DOI: 10.1002/9780470057339.vat003

Encyclopedia of Environmetrics

Encyclopedia of Environmetrics

How to Cite

Coull, B. A. and Holmes, L. B. 2006. Teratogenesis, Environmental. Encyclopedia of Environmetrics. 6.

Author Information

  1. 1

    Harvard University, MA, USA

  2. 2

    Massachusetts General Hospital, MA, USA

Publication History

  1. Published Online: 15 SEP 2006


Teratogenesis is defined as the induction of malformations or defects in fetuses during gestation or at birth. As one might expect, induction of birth defects is a major public health concern. Many of these birth defects are attributed to the process of multifactorial inheritance in which both genetic and nongenetic factors are presumed to be involved. Unfortunately, the large majority of the nongenetic factors remain unidentified.