Published Online: 15 SEP 2006
Copyright © 2002 John Wiley & Sons, Ltd
Encyclopedia of Environmetrics
How to Cite
Seillier-moiseiwitsch, F. and Niu, T. 2006. Transmission/Disequilibrium Test. Encyclopedia of Environmetrics. 6.
- Published Online: 15 SEP 2006
The transmission/disequilibrium test (TDT) can be utilized as a test of linkage between a marker and a disease locus or as a test of association between these loci. It relies on the marker information from triads consisting of parents and their affected child. Its properties depend on the purpose it is used for. Its validity for stratified populations makes it particularly attractive. Also, it is often more powerful than allele-sharing methods for complex diseases.