Chapter 16. Combining Quantitative Trait and Gene-Expression Data
- Michael R. Barnes
Published Online: 21 MAR 2007
DOI: 10.1002/9780470059180.ch16
Copyright © 2007 John Wiley & Sons, Ltd
Book Title
Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data, Second Edition
Additional Information
How to Cite
Chesler, E. J. (2007) Combining Quantitative Trait and Gene-Expression Data, in Bioinformatics for Geneticists: A Bioinformatics Primer for the Analysis of Genetic Data, Second Edition (ed M. R. Barnes), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470059180.ch16
Editor Information
Bioinformatics, GlaxoSmithKline Pharmaceuticals, Third Avenue, Harlow, Essex, UK
Publication History
- Published Online: 21 MAR 2007
- Published Print: 9 MAR 2007
ISBN Information
Print ISBN: 9780470026199
Online ISBN: 9780470059180
- Summary
- Chapter
Keywords:
- combining quantitative trait and gene-expression data;
- data transformations and mapping quality;
- genetic analysis and mapping models;
- systems genetic analysis;
- expression QTL analysis
Summary
This chapter contains sections titled:
Introduction: the genetic regulation of endophenotypes
Transcript abundance as a complex phenotype
Scaling up genetic analysis and mapping models for microarrays
Genetic correlation analysis
Systems genetic analysis
Using expression QTLs to identify candidate genes for the regulation of complex phenotypes
Conclusions
References