Chapter 16. The Use of Benzodiazepines in Organophosphorus Nerve Agent Intoxication

  1. Timothy C. Marrs OBE, MD, DSc, FRCP, FRCPath2,3,4,
  2. Robert L. Maynard CBE, FRCP, FRCPath5 and
  3. Frederick R. Sidell MD6
  1. Timothy C. Marrs OBE, MD, DSc, FRCP, FRCPath2,3,4 and
  2. Åke Sellström1

Published Online: 2 APR 2007

DOI: 10.1002/9780470060032.ch16

Chemical Warfare Agents: Toxicology and Treatment, Second Edition

Chemical Warfare Agents: Toxicology and Treatment, Second Edition

How to Cite

Marrs, T. C. and Sellström, Å. (2007) The Use of Benzodiazepines in Organophosphorus Nerve Agent Intoxication, in Chemical Warfare Agents: Toxicology and Treatment, Second Edition (eds T. C. Marrs, R. L. Maynard and F. R. Sidell), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470060032.ch16

Editor Information

  1. 2

    Edentox Associates, Pinehurst, Four Elms Road, Edenbridge, Kent TN8 6AQ, UK

  2. 3

    National Poisons Information Service (Birmingham Centre) and West Midlands Poisons Unit, City Hospital, Birmingham B18 7QH, UK

  3. 4

    Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, PR1 2HE, UK

  4. 5

    Health Protection Agency, Chilton, Didcot, Oxfordshire OX11 0RQ, UK

  5. 6

    US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA

Author Information

  1. 1

    Swedish Defence Research Institute, S-90182 Umeå, Sweden

  2. 2

    Edentox Associates, Pinehurst, Four Elms Road, Edenbridge, Kent TN8 6AQ, UK

  3. 3

    National Poisons Information Service (Birmingham Centre) and West Midlands Poisons Unit, City Hospital, Birmingham B18 7QH, UK

  4. 4

    Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, PR1 2HE, UK

Publication History

  1. Published Online: 2 APR 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470013595

Online ISBN: 9780470060032

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Keywords:

  • benzodiazepine use in nerve agent intoxication;
  • diazepam and nerve agents;
  • diazepam and avizafone in sarin-induced neuropathology;
  • benzodiazepine dose recommendation;
  • lorazepam efficacy in status epilepticus

Summary

This chapter contains sections titled:

  • Introduction

  • Benzodiazepines

  • Clinical Studies

  • Indications and Dosage for Use of Diazepam

  • Conclusions

  • References