Chapter 2. The Physicochemical Properties and General Toxicology of Chemical Warfare Agents

  1. Timothy C. Marrs OBE, MD, DSc, FRCP, FRCPath1,2,3,
  2. Robert L. Maynard CBE, FRCP, FRCPath4 and
  3. Frederick R. Sidell MD5
  1. Robert L. Maynard CBE, FRCP, FRCPath

Published Online: 2 APR 2007

DOI: 10.1002/9780470060032.ch2

Chemical Warfare Agents: Toxicology and Treatment, Second Edition

Chemical Warfare Agents: Toxicology and Treatment, Second Edition

How to Cite

Maynard, R. L. (2007) The Physicochemical Properties and General Toxicology of Chemical Warfare Agents, in Chemical Warfare Agents: Toxicology and Treatment, Second Edition (eds T. C. Marrs, R. L. Maynard and F. R. Sidell), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470060032.ch2

Editor Information

  1. 1

    Edentox Associates, Pinehurst, Four Elms Road, Edenbridge, Kent TN8 6AQ, UK

  2. 2

    National Poisons Information Service (Birmingham Centre) and West Midlands Poisons Unit, City Hospital, Birmingham B18 7QH, UK

  3. 3

    Lancashire School of Health and Postgraduate Medicine, University of Central Lancashire, Preston, PR1 2HE, UK

  4. 4

    Health Protection Agency, Chilton, Didcot, Oxfordshire OX11 0RQ, UK

  5. 5

    US Army Medical Research Institute of Chemical Defense, Aberdeen Proving Ground, MD 21010-5400, USA

Author Information

  1. Health Protection Agency, Chilton, Didcot, Oxfordshire OX11 0RQ, UK

Publication History

  1. Published Online: 2 APR 2007
  2. Published Print: 23 MAR 2007

ISBN Information

Print ISBN: 9780470013595

Online ISBN: 9780470060032

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Keywords:

  • Chemical warfare (CW) agents - solids, liquids or gases;
  • general toxicology of CW agents;
  • liquid aerosol fate;
  • International Radiological Protection Commission (IRPC) Task Force on Lung Dynamics;
  • impaction and particle sizing

Summary

This chapter contains sections titled:

  • Gases and Vapours

  • Units Used to Describe the Concentrations of Gases

  • Behaviour of Liquid Agents

  • Behaviour of Solutions of Agents

  • Behaviour of Aerosols

  • Fate of Liquid Aerosols

  • Mathematical Description of Aerosols

  • Deposition of Airborne Particles in the Respiratory Tract

  • Mechanisms of Particle Deposition

  • Aerodynamic Diameter

  • Hygroscopic Growth of and Neutralization of Acidic Droplets in the Airways

  • Neutralization of Acid Droplets by Ammonia in the Respiratory Tract

  • General Concepts Concerning the Toxicity of CW Agents

  • Absorption of Gases

  • Particles as Vectors for Chemical Warfare Agents

  • References