22. Mathematical Models in Population Genetics

  1. D. J. Balding2,
  2. M. Bishop3 and
  3. C. Cannings4
  1. C. Neuhauser

Published Online: 9 MAY 2008

DOI: 10.1002/9780470061619.ch22

Handbook of Statistical Genetics, Third Edition

Handbook of Statistical Genetics, Third Edition

How to Cite

Neuhauser, C. (2007) Mathematical Models in Population Genetics, in Handbook of Statistical Genetics, Third Edition (eds D. J. Balding, M. Bishop and C. Cannings), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470061619.ch22

Editor Information

  1. 2

    Imperial College of Science, Technology and Medicine, London, UK

  2. 3

    CNR-ITB, Milan, Italy

  3. 4

    Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Author Information

  1. Department of Ecology, Evolution and Behavior, University of Minnesota, Saint Paul, MN, USA

Publication History

  1. Published Online: 9 MAY 2008
  2. Published Print: 24 AUG 2007

ISBN Information

Print ISBN: 9780470058305

Online ISBN: 9780470061619



  • random mating and genetic drift;
  • Hardy–Weinberg equilibrium;
  • gene frequency;
  • infinite allele model;
  • genealogical relationships and population dynamics;
  • coalescent theory;
  • molecular differences and molecular evolution;
  • neutrality–selectionist controversy


This chapter contains sections titled:

  • A Brief History of The Role of Selection

  • Mutation, Random Genetic Drift, and Selection

  • The Diffusion Approximation

  • The Infinite Allele Model

  • Other Models of Mutation and Selection

  • Coalescent Theory

  • Detecting Selection

  • Acknowledgments

  • References