25. Coalescent Theory

  1. D. J. Balding2,
  2. M. Bishop3 and
  3. C. Cannings4
  1. M. Nordborg

Published Online: 9 MAY 2008

DOI: 10.1002/9780470061619.ch25

Handbook of Statistical Genetics, Third Edition

Handbook of Statistical Genetics, Third Edition

How to Cite

Nordborg, M. (2007) Coalescent Theory, in Handbook of Statistical Genetics, Third Edition (eds D. J. Balding, M. Bishop and C. Cannings), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470061619.ch25

Editor Information

  1. 2

    Imperial College of Science, Technology and Medicine, London, UK

  2. 3

    CNR-ITB, Milan, Italy

  3. 4

    Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Author Information

  1. Molecular and Computational Biology, University of Southern California, Los Angeles, CA, USA

Publication History

  1. Published Online: 9 MAY 2008
  2. Published Print: 24 AUG 2007

ISBN Information

Print ISBN: 9780470058305

Online ISBN: 9780470061619

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Keywords:

  • Wright–Fisher neutral evolution model;
  • most recent common ancestor;
  • continuous-time Markov process;
  • genomic polymorphism data;
  • pergeneration migration probabilities;
  • Mendelian segregation;
  • chromosomal lineages;
  • genealogical distortion;
  • neutral mutations;
  • phylogenetic inference

Summary

This chapter contains sections titled:

  • Introduction

  • The coalescent

  • Generalizing the Coalescent

  • Geographical Structure

  • Segregation

  • Recombination

  • Selection

  • Neutral Mutations

  • Conclusion

  • Acknowledgments

  • References