29. Analysis of Population Subdivision

  1. D. J. Balding2,
  2. M. Bishop3 and
  3. C. Cannings4
  1. L. Excoffier

Published Online: 9 MAY 2008

DOI: 10.1002/9780470061619.ch29

Handbook of Statistical Genetics, Third Edition

Handbook of Statistical Genetics, Third Edition

How to Cite

Excoffier, L. (2007) Analysis of Population Subdivision, in Handbook of Statistical Genetics, Third Edition (eds D. J. Balding, M. Bishop and C. Cannings), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470061619.ch29

Editor Information

  1. 2

    Imperial College of Science, Technology and Medicine, London, UK

  2. 3

    CNR-ITB, Milan, Italy

  3. 4

    Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Author Information

  1. Zoological Institute, Department of Biology, University of Berne, Berne, Switzerland

Publication History

  1. Published Online: 9 MAY 2008
  2. Published Print: 24 AUG 2007

ISBN Information

Print ISBN: 9780470058305

Online ISBN: 9780470061619



  • ANOVA – analysis of variance;
  • fixation index;
  • Wahlund effect;
  • coancestry and kinship coefficient;
  • Bayesian estimation;
  • AMOVA – analysis of molecular variance;
  • restriction fragment length polymorphism;
  • Euclidean distances;
  • multiallelic molecular data;
  • stepwise mutation model


This chapter contains sections titled:

  • Introduction

  • The Fixation Index F

  • Wright's F Statistics in Hierarchic Subdivisions

  • Analysis of Genetic Subdivision Under an Analysis of Variance Framework

  • Relationship Between Different Definitions of Fixation Indexes

  • F Statistics and Coalescence Times

  • Analysis of Molecular Data: The Amova Framework

  • Significance Testing

  • Related and Remaining Problems

  • Acknowledgments

  • References