32. Epidemiology and Genetic Epidemiology

  1. D. J. Balding2,
  2. M. Bishop3 and
  3. C. Cannings4
  1. P. R. Burton,
  2. J. M. Bowden and
  3. M. D. Tobin

Published Online: 9 MAY 2008

DOI: 10.1002/9780470061619.ch32

Handbook of Statistical Genetics, Third Edition

Handbook of Statistical Genetics, Third Edition

How to Cite

Burton, P. R., Bowden, J. M. and Tobin, M. D. (2007) Epidemiology and Genetic Epidemiology, in Handbook of Statistical Genetics, Third Edition (eds D. J. Balding, M. Bishop and C. Cannings), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470061619.ch32

Editor Information

  1. 2

    Imperial College of Science, Technology and Medicine, London, UK

  2. 3

    CNR-ITB, Milan, Italy

  3. 4

    Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Author Information

  1. Departments of Health Sciences and Genetics, University of Leicester, Leicester, UK

Publication History

  1. Published Online: 9 MAY 2008
  2. Published Print: 24 AUG 2007

ISBN Information

Print ISBN: 9780470058305

Online ISBN: 9780470061619



  • epidemiological genetics;
  • population-averaged interpretation;
  • generalised linear mixed model and estimating equations;
  • polygenic additive and dominance effects;
  • first-order Markov process;
  • Li–Mantel estimator;
  • classical ascertainment bias;
  • Poisson likelihoods;
  • dynamic allele specific hybridisation


This chapter contains sections titled:

  • Introduction

  • Descriptive Epidemiology

  • Descriptive Genetic Epidemiology

  • Studies Investigating Specific Aetiological Determinants

  • The Future

  • Acknowledgments

  • References