37. Whole Genome Association

  1. D. J. Balding2,
  2. M. Bishop3 and
  3. C. Cannings4
  1. A. P. Morris and
  2. L. R. Cardon

Published Online: 9 MAY 2008

DOI: 10.1002/9780470061619.ch37

Handbook of Statistical Genetics, Third Edition

Handbook of Statistical Genetics, Third Edition

How to Cite

Morris, A. P. and Cardon, L. R. (2007) Whole Genome Association, in Handbook of Statistical Genetics, Third Edition (eds D. J. Balding, M. Bishop and C. Cannings), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470061619.ch37

Editor Information

  1. 2

    Imperial College of Science, Technology and Medicine, London, UK

  2. 3

    CNR-ITB, Milan, Italy

  3. 4

    Division of Genomic Medicine, University of Sheffield, Sheffield, UK

Author Information

  1. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK

Publication History

  1. Published Online: 9 MAY 2008
  2. Published Print: 24 AUG 2007

ISBN Information

Print ISBN: 9780470058305

Online ISBN: 9780470061619

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Keywords:

  • Mendelian disorders;
  • genotyping and functional polymorphism;
  • age-related macular degeneration;
  • Cochran–Armitage test statistic;
  • false discovery rate;
  • Bayesian Markov chain Monte Carlo;
  • Haplotype-based analyses;
  • human genetic variants

Summary

This chapter contains sections titled:

  • Introduction

  • Genotype Quality Control

  • Single-Locus Analysis

  • Population Structure

  • Multi-Locus Analysis

  • Epistasis

  • Replication

  • Prospects for Whole-Genome Association Studies

  • References