19. Brain-Implantable Biomimetic Electronics as Neural Prostheses to Restore Lost Cognitive Function

  1. Metin Akay Bachelor of Science, Master of Science in Electrical Engineering, Ph.D. professor chairman author coauthor editor chair guest editor fellow senior member member
  1. Theodore W. Berger1,
  2. Ashish Ahuja2,
  3. Spiros H. Courellis1,
  4. Gopal Erinjippurath1,
  5. Ghassan Gholmieh1,
  6. John J. Granacki1,
  7. Min Chi Hsaio1,
  8. Jeff LaCoss3,
  9. Vasilis Z. Marmarelis1,
  10. Patrick Nasiatka2,
  11. Vijay Srinivasan2,
  12. Dong Song1,
  13. Armand R. Tanguay1 and
  14. Jack Wills2

Published Online: 10 APR 2006

DOI: 10.1002/9780470068298.ch19

Handbook of Neural Engineering

Handbook of Neural Engineering

How to Cite

Berger, T. W., Ahuja, A., Courellis, S. H., Erinjippurath, G., Gholmieh, G., Granacki, J. J., Hsaio, M. C., LaCoss, J., Marmarelis, V. Z., Nasiatka, P., Srinivasan, V., Song, D., Tanguay, A. R. and Wills, J. (2006) Brain-Implantable Biomimetic Electronics as Neural Prostheses to Restore Lost Cognitive Function, in Handbook of Neural Engineering (ed M. Akay), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470068298.ch19

Editor Information

  1. Scottsdale, Arizona, USA

Author Information

  1. 1

    Department of Biomedical Engineering, University of Southern California, Los Angeles, California, USA

  2. 2

    Department of Electrical Engineering, University of Southern California, Los Angeles, California, USA

  3. 3

    Information Sciences Institute, University of Southern California, Los Angeles, California, USA

Publication History

  1. Published Online: 10 APR 2006
  2. Published Print: 20 DEC 2006

ISBN Information

Print ISBN: 9780470056691

Online ISBN: 9780470068298

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Keywords:

  • brain-implantable biomimetic electronics as neural prostheses;
  • hippocampal trisynaptic pathway of nonlinear properties;
  • microcircuitry implementation of ca3 input/output model

Summary

This chapter contains sections titled:

  • Introduction

  • The System: Hippocampus

  • General Strategy and System Requirements

  • Proof of Concept: Replacement of CA3 Region of Hippocampal Slice with Biomimetic Device

  • Experimental Characterization of Nonlinear Properties of the Hippocampal Trisynaptic Pathway

  • Nonlinear Dynamic Modeling of CA3 Input/Output Properties

  • Microcircuitry Implementation of CA3 Input/Output Model

  • Conformal, Multisite Electrode Array Interface

  • System Integration: Restoration of Hippocampal Trisynaptic Circuit Dynamics with CA3 Prosthesis

  • Acknowledgments

  • References