APPENDIX 4A Statistical Analysis

  1. John Kloke,
  2. Johanna Hardin

Published Online: 1 OCT 2008

DOI: 10.1002/9780470089941.eta04as00

Current Protocols Essential Laboratory Techniques

Current Protocols Essential Laboratory Techniques

How to Cite

Kloke, J. and Hardin, J. 2008. Statistical Analysis. Current Protocols Essential Laboratory Techniques. 00:4A:A.4A.1–A.4A.30.

Author Information

  1. Pomona College, Claremont, California

Publication History

  1. Published Online: 1 OCT 2008
  2. Published Print: JAN 2008


In this Appendix, we provide an outline of methods used in analyzing molecular biology data. We give a summary of types of data encountered and the appropriate methods to apply for the questions of interest. Statistical techniques described include the t test, the Wilcoxon rank sum test, the Mann-Whitney-Wilcoxon test, ANOVA, regression, and the chi-square test. For each method, we give the appropriate assumptions, the details of the test, and a complete concrete example to follow. We also discuss related ideas such as multiple comparisons and why correlation does not imply causation.


  • Data Analysis;
  • Hypothesis Testing;
  • Confidence Intervals