Chapter 12. Enantioselective Addition of Organozinc Compounds

  1. Professor Zvi Rappoport3 and
  2. Ilan Marek4
  1. Kenso Soai1,
  2. Tsuneomi Kawasaki1 and
  3. Itaru Sato2

Published Online: 4 SEP 2007

DOI: 10.1002/9780470093399.ch12

The Chemistry of Organozinc Compounds

The Chemistry of Organozinc Compounds

How to Cite

Soai, K., Kawasaki, T. and Sato, I. (2006) Enantioselective Addition of Organozinc Compounds, in The Chemistry of Organozinc Compounds (eds Z. Rappoport and I. Marek), John Wiley & Sons, Ltd, Chichester, UK. doi: 10.1002/9780470093399.ch12

Editor Information

  1. 3

    The Hebrew University, Jerusalem, Israel

  2. 4

    Technion-Israel Institute of Technology, Haifa, Israel

Author Information

  1. 1

    Department of Applied Chemistry, Faculty of Science, Tokyo University of Science, Kagurazaka, Shinjuku-ku, Tokyo 162-8601, Japan

  2. 2

    Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, Sanda, Hyogo 669-1337, Japan.

Publication History

  1. Published Online: 4 SEP 2007
  2. Published Print: 27 OCT 2006

Book Series:

  1. PATAI'S Chemistry of Functional Groups

Book Series Editors:

  1. Professor Saul Patai and
  2. Professor Zvi Rappoport

Series Editor Information

  1. The Hebrew University, Jerusalem, Israel

ISBN Information

Print ISBN: 9780470093375

Online ISBN: 9780470093399

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Keywords:

  • catalytic enantioselective synthesis;
  • asymmetric amplification and organozinc enantioselective addition;
  • enantioselective alkenylation;
  • asymmetric amplification;
  • Katsuki-Sharpless asymmetric allyl alcohol epoxidation;
  • asymmetric autocatalysis and chirality amplification;
  • enantioenriched alcohol preparation

Summary

This chapter contains sections titled:

  • Introduction

  • The Mechanism of Catalysis for Diorganozinc Addition to Carbonyl Compounds

  • Enantioselective Addition of Organozincs to Carbonyl Compounds

  • Enantioselective Addition of Diorganozincs to Imine Derivatives

  • Asymmetric Amplification

  • Asymmetric Autocatalysis in the Asymmetric Addition of Dialkylzincs to Aldehydes

  • Conclusion

  • Acknowledgment

  • References