Proteinase-Catalyzed Synthesis of Peptide Bonds

  1. Alton Meister
  1. Joseph S. Fruton

Published Online: 22 NOV 2006

DOI: 10.1002/9780470122983.ch7

Advances in Enzymology and Related Areas of Molecular Biology, Volume 53

Advances in Enzymology and Related Areas of Molecular Biology, Volume 53

How to Cite

Fruton, J. S. (1982) Proteinase-Catalyzed Synthesis of Peptide Bonds, in Advances in Enzymology and Related Areas of Molecular Biology, Volume 53 (ed A. Meister), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470122983.ch7

Editor Information

  1. Cornell University Medical Colloge, New York, New York

Author Information

  1. Yale University, New Haven, Connecticut

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1982

ISBN Information

Print ISBN: 9780471084051

Online ISBN: 9780470122983

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Keywords:

  • peptide bond proteinase-catalyzed synthesis;
  • serine proteinases;
  • thiol proteinases;
  • metalloproteinases;
  • acid proteinases

Summary

This chapter contains sections titled:

  • Introduction

  • Historical Background

  • Thermodynamics of Peptide Bond Synthesis

  • Peptide Bond Synthesis by Aminolysis of Amides and Esters

  • Specificity in the Enzymatic Synthesis of Peptide Bonds

  • Peptide Bond Synthesis by Serine Proteinases

  • Peptide Bond Synthesis by Thiol Proteinases

  • Peptide Bond Synthesis by Metalloproteinases

  • Peptide Bond Synthesis by Acid Proteinases

  • Conclusion