Ligand Substitution Chemistry and Enzymology

  1. Alton Meister
  1. W. Terry Jenkins

Published Online: 22 NOV 2006

DOI: 10.1002/9780470122983.ch8

Advances in Enzymology and Related Areas of Molecular Biology, Volume 53

Advances in Enzymology and Related Areas of Molecular Biology, Volume 53

How to Cite

Jenkins, W. T. (1982) Ligand Substitution Chemistry and Enzymology, in Advances in Enzymology and Related Areas of Molecular Biology, Volume 53 (ed A. Meister), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470122983.ch8

Editor Information

  1. Cornell University Medical Colloge, New York, New York

Author Information

  1. Department of Chemistry, Indiana University, Bloomington, Indiana

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1982

ISBN Information

Print ISBN: 9780471084051

Online ISBN: 9780470122983

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Keywords:

  • ligand substitution chemistry;
  • enzyme complex formation;
  • characteristic kinetic properties of surrogates;
  • maximum velocity;
  • surrogate binding sites

Summary

This chapter contains sections titled:

  • Introduction

  • What Limits an Enzymatic Reaction

  • Generalizations of Ligand Substitution Chemistry

  • Enzyme Kinetics with Ligand Substitution Reactions

  • Ligand Reactions Associated with Covalent Bond Cleavage

  • Discussion