Ribonucleotide Reductases

  1. Alton Meister
  1. Joanne Stubbe

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123096.ch6

Advances in Enzymology and Related Areas of Molecular Biology, Volume 63

Advances in Enzymology and Related Areas of Molecular Biology, Volume 63

How to Cite

Stubbe, J. (2006) Ribonucleotide Reductases, in Advances in Enzymology and Related Areas of Molecular Biology, Volume 63 (ed A. Meister), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123096.ch6

Editor Information

  1. Cornell University Medical College, New York, New York

Author Information

  1. Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1990

ISBN Information

Print ISBN: 9780471509844

Online ISBN: 9780470123096

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Keywords:

  • ribonucleotide reductases (RDPR);
  • half-sites reactivity;
  • AdoCbl dependent RTPR;
  • eucaryotic ribonucleotide reductases;
  • inhibitors of RDPR

Summary

This chapter contains sections titled:

  • Introduction

  • E. coli Reductase: Structure and Function of the Binuclear Iron Center

  • Subunit Interaction and Half-Sites Reactivity

  • Model for Transcriptional Regulation of E. coli RDPR

  • Mechanistic Investigations on RDPR

  • AdoCbl Dependent RTPR

  • Mn Dependent RNR

  • Eucaryotic Ribonucleotide Reductases

  • Inhibitors of RDPR