γ-Glutamyl Transpeptidase: Catalytic Mechanism and Gene Expression

  1. Daniel L. Purich
  1. Naoyuki Taniguchi,
  2. Yoshitaka Ikeda

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123188.ch7

Book Title

Advances in Enzymology and Related Areas of Molecular Biology: Amino Acid Metabolism, Part A, Volume 72

Advances in Enzymology and Related Areas of Molecular Biology: Amino Acid Metabolism, Part A, Volume 72

Additional Information

How to Cite

Taniguchi, N. and Ikeda, Y. (2006) γ-Glutamyl Transpeptidase: Catalytic Mechanism and Gene Expression, in Advances in Enzymology and Related Areas of Molecular Biology: Amino Acid Metabolism, Part A, Volume 72 (ed D. L. Purich), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123188.ch7

Editor Information

  1. University of Florida College of Medicine, Gainesville, Florida

Author Information

  1. The Department of Biochemistry, Osaka University Medical School, Suita, Osaka 565, Japan

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1998

ISBN Information

Print ISBN: 9780471246435

Online ISBN: 9780470123188

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CHAPTER TOOLS

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Keywords:

  • bacterial lysine biosynthesis;
  • aspartate semialdehyde dehydrogenase;
  • dihydrodipicolinate reductase & synthase;
  • D,L-diaminopimelate decarboxylase;
  • D,L-diaminopimelate dehydrogenase

Summary

  • Introduction

  • Structural and Topological Features of γ-Glutamyl Transpeptidase

  • Biosynthesis and Processing of γ-Glutamyl Transpeptidase

  • Role of γ-Glutamyl Transpeptidase in Glutathione Metabolism

  • Reactions Catalyzed by γ-Glutamyl Transpeptidase and Substrate Specificity

  • Active site of γ-Glutamyl Transpeptidase

  • γ-Glutamyl Transpeptidase-Related Enzyme and γ-Glutamyl Transpeptidase Transcripts Unique to Human Lung

  • Gene Structure and Expression

  • Cancer-Associated Changes of γ-Glutamyl Transpeptidase

  • Conclusion

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