Rethinking Fundamentals of Enzyme Action

  1. Daniel L. Purich
  1. Dexter B. Northrop

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123195.ch2

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

How to Cite

Northrop, D. B. (2006) Rethinking Fundamentals of Enzyme Action, in Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73 (ed D. L. Purich), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123195.ch2

Editor Information

  1. University of Florida College of Medicine, Gainesville, Florida

Author Information

  1. Division of Pharmaceutical Sciences, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53706

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1999

ISBN Information

Print ISBN: 9780471246442

Online ISBN: 9780470123195

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Keywords:

  • enzyme action;
  • michaelian kinetics of steady state;
  • catalytic power;
  • algebraic vs graphic analogies;
  • mutant enzymes

Summary

This chapter contains sections titled:

  • Introduction

  • Michaelian Kinetics in the Steady State

  • Algebraic Definition of V/K

  • Physiological Significance of V/K

  • Problems in Defining Catalytic Power

  • The Congruent Thermodynamic Cycle

  • Kinetics of Congruency

  • Origins of Catalytic Power

  • Algebraic Versus Graphic Analogies

  • Resolution of Conflicts