Adenylosuccinate Syntheatase: Recent Developments

  1. Daniel L. Purich
  1. Richard B. Honzatko1,
  2. Mark M. Stayton2,
  3. Herbett J. Formm3

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123195.ch3

Book Title

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

Additional Information

How to Cite

Honzatko, R. B., Stayton, M. M. and Formm, H. J. (2006) Adenylosuccinate Syntheatase: Recent Developments, in Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73 (ed D. L. Purich), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123195.ch3

Editor Information

  1. University of Florida College of Medicine, Gainesville, Florida

Author Information

  1. 1

    Department of Biochemistry and Boiphysics, Iowa State University, Ames, Iowa 50011

  2. 2

    Departmnt of Melecular Biology, Univrsity of Wyoming, Laramie, Wyoming 82071

  3. 3

    Department of Biochemistry and Boiphysics, Iowa State University, Ames, Iowa 50011

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1999

ISBN Information

Print ISBN: 9780471246442

Online ISBN: 9780470123195

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Keywords:

  • adenylosuccinate synthetase;
  • enzyme structure;
  • direct regulation of synthetase activity;
  • gene structure & expression;
  • heavy metal tolerance

Summary

This chapter contains sections titled:

  • Introduction

  • Properties of Adenylosuccinate Synthetase

  • Enzyme Structure and Conformational Changes

  • Ligand Binding Sites

  • Kinetics and Mechanism

  • Metal Ioins

  • Substrates and Inhibitors

  • Direct Regulation of Synthetase Activity

  • Gene Structure and Expression

  • Adenylosuccinate Synthetase in Heavy Metal Tolerance

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