Nucleoside Monophosphate Kinases: Structure, Mechanism, and Substrate Specificity

  1. Daniel L. Purich
  1. Honggao Yan1,
  2. Ming-Daw Tsai2

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123195.ch4

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73

How to Cite

Yan, H. and Tsai, M.-D. (2006) Nucleoside Monophosphate Kinases: Structure, Mechanism, and Substrate Specificity, in Advances in Enzymology and Related Areas of Molecular Biology: Mechanism of Enzyme Action, Part A, Volume 73 (ed D. L. Purich), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123195.ch4

Editor Information

  1. University of Florida College of Medicine, Gainesville, Florida

Author Information

  1. 1

    Department of Biochemistry, Michigan State University, East Lansing, Michigan 48824

  2. 2

    Departments of Chemistry and Biochemistry, Ohio State University, Columbus, Ohio 43210

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 1999

ISBN Information

Print ISBN: 9780471246442

Online ISBN: 9780470123195

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Keywords:

  • nucleoside monophosphate kinases;
  • nucleotide specificity;
  • substrate-induced conformational changes;
  • substrate specificity;
  • phosphoryl transfer

Summary

This chapter contains sections titled:

  • Introduction

  • Primary Structure

  • Tertiary Structure

  • Catalytic Mechanism

  • Structural Basis of Nucleotide Specificity

  • Substrate-Induced Conformational Changes