Phosphotriesterase: An Enzyme in Search of Its Natural Substrate

  1. Daniel L. Purich
  1. Frank M. Raushel1,
  2. Hazel M. Holden2

Published Online: 22 NOV 2006

DOI: 10.1002/9780470123201.ch2

Advances in Enzymology and Related Areas of Molecular Biology, Volume 74

Advances in Enzymology and Related Areas of Molecular Biology, Volume 74

How to Cite

Raushel, F. M. and Holden, H. M. (2006) Phosphotriesterase: An Enzyme in Search of Its Natural Substrate, in Advances in Enzymology and Related Areas of Molecular Biology, Volume 74 (ed D. L. Purich), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470123201.ch2

Editor Information

  1. University of Florida College of Medicine, Gainesville, Florida

Author Information

  1. 1

    Department of Chemistry, Texas A&M University, College Station, Texas 77843

  2. 2

    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin 53706

Publication History

  1. Published Online: 22 NOV 2006
  2. Published Print: 1 JAN 2000

ISBN Information

Print ISBN: 9780471349211

Online ISBN: 9780470123201

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Keywords:

  • phosphotriesterase;
  • protein sequence;
  • mutagenesis of active site residues;
  • stereochemistry at phosphorus center;
  • substrate specificity

Summary

This chapter contains sections titled:

  • Introduction

  • Structure

  • Mechanism of Action

  • Substrate Specificity

  • Summary