10. Surface-Charged Poly(Lactide-Co-Glycolide) Microparticles as Novel Antigen Delivery Systems

  1. Manmohan Singh M. Pharm., Ph.D.
  1. Manmohan Singh M. Pharm., Ph.D.,
  2. James Chesko,
  3. Jina Kazzaz,
  4. Mildred Ugozolli,
  5. Padma Malyala and
  6. Derek T. O'Hagan

Published Online: 2 NOV 2006

DOI: 10.1002/9780470134931.ch10

Vaccine Adjuvants and Delivery Systems

Vaccine Adjuvants and Delivery Systems

How to Cite

Singh, M., Chesko, J., Kazzaz, J., Ugozolli, M., Malyala, P. and O'Hagan, D. T. (2007) Surface-Charged Poly(Lactide-Co-Glycolide) Microparticles as Novel Antigen Delivery Systems, in Vaccine Adjuvants and Delivery Systems (ed M. Singh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470134931.ch10

Editor Information

  1. Novartis Vaccines, Emeryville, California, USA

Author Information

  1. Novartis Vaccines, Emeryville, California, USA

Publication History

  1. Published Online: 2 NOV 2006
  2. Published Print: 15 JUN 2007

ISBN Information

Print ISBN: 9780471739074

Online ISBN: 9780470134931

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Keywords:

  • surface-charged poly(lactide-co-glycolide) microparticles;
  • charged microparticles for induction;
  • mucosal immunization with microparticles

Summary

This chapter contains sections titled:

  • Introduction

  • Microparticles as Adjuvants

  • Charged Microparticles for Antibody Induction to Adsorbed Protein Antigens

  • Charged Microparticles for the Induction of Cell-Mediated Immunity

  • Cationic Microparticles as Delivery Systems for DNA Vaccines

  • Charged Microparticles as Delivery Systems for Adjuvants

  • Mucosal Immunization with Microparticles

  • Mechanism of Action of Charged PLG Microparticle Formulations

  • Future Prospects

  • Summary

  • Acknowledgments

  • References