2. Antigen Processing and Presentation

  1. Manmohan Singh M. Pharm., Ph.D.
  1. Subash Sad

Published Online: 2 NOV 2006

DOI: 10.1002/9780470134931.ch2

Vaccine Adjuvants and Delivery Systems

Vaccine Adjuvants and Delivery Systems

How to Cite

Sad, S. (2007) Antigen Processing and Presentation, in Vaccine Adjuvants and Delivery Systems (ed M. Singh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470134931.ch2

Editor Information

  1. Novartis Vaccines, Emeryville, California, USA

Author Information

  1. Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada

Publication History

  1. Published Online: 2 NOV 2006
  2. Published Print: 15 JUN 2007

ISBN Information

Print ISBN: 9780471739074

Online ISBN: 9780470134931



  • antigen processing and adjuvants;
  • antigen exposure and memory generation;
  • T-cell memory and protective efficacy


This chapter contains sections titled:

  • Introduction

  • Recognition and Uptake

  • Dendritic Cell Activation

  • Antigen Presentation and Cross-Presentation

  • MHC Class I-Restricted Antigen Presentation

  • MHC Class II-Restricted Antigen Presentation

  • Antigen Processing and Adjuvants

  • Influence of the Type of Antigen-Presenting Cell

  • T-Cell Priming

  • Generation of Memory

  • Phenotypes of Memory

  • T-Cell Memory and Protective Efficacy

  • References