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Chapter 11. Dihydropyridine Calcium Channel Blockers for Hypertension

  1. Douglas S. Johnson,
  2. Jie Jack Li
  1. Daniel P. Christen

Published Online: 2 NOV 2006

DOI: 10.1002/9780470134979.ch11

The Art of Drug Synthesis

The Art of Drug Synthesis

How to Cite

Christen, D. P. (2006) Dihydropyridine Calcium Channel Blockers for Hypertension, in The Art of Drug Synthesis (eds D. S. Johnson and J. J. Li), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470134979.ch11

Editor Information

  1. Pfizer Global Research and Development, Ann Arbor, Michigan, USA

Author Information

  1. Transtech Pharma, High Point, North Carolina, USA

Publication History

  1. Published Online: 2 NOV 2006
  2. Published Print: 20 JUN 2007

ISBN Information

Print ISBN: 9780471752158

Online ISBN: 9780470134979

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Keywords:

  • dihydropyridine calcium channel blockers;
  • racemic felodipine synthesis;
  • amlodipine besylate (NORVASC) synthesis

Summary

This chapter contains sections titled:

  • Introduction

  • Synthesis of Nifedipine (Adalat®)

  • Synthesis of Felodepine (Plendil®)

  • Synthesis of Amlodipine Besylate (Norvasc®)

  • Synthesis of Azelnidipine (Calblock®)

  • References