4. Limited Proteolysis Mass Spectrometry of Protein Complexes

  1. Kevin M. Downard
  1. Maria Monti and
  2. Piero Pucci

Published Online: 7 DEC 2006

DOI: 10.1002/9780470146330.ch4

Mass Spectrometry of Protein Interactions

Mass Spectrometry of Protein Interactions

How to Cite

Monti, M. and Pucci, P. (2007) Limited Proteolysis Mass Spectrometry of Protein Complexes, in Mass Spectrometry of Protein Interactions (ed K. M. Downard), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470146330.ch4

Editor Information

  1. School of Molecular and Microbial Biosciences, The University of Sydney, Australia

Author Information

  1. Dipartimento di Chimica Organica e Biochimica, Università di Napoli “Federico II,” Napoli, Italy

Publication History

  1. Published Online: 7 DEC 2006
  2. Published Print: 26 JUL 2007

ISBN Information

Print ISBN: 9780471793731

Online ISBN: 9780470146330

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Keywords:

  • limited proteolysis mass spectrometry of protein complexes;
  • probing protein–ligand interactions;
  • protein flexibility to exploit catalytic activity

Summary

This chapter contains sections titled:

  • Introduction

  • Limited Proteolysis Analysis

  • Experimental Design

  • Probing Protein–Protein Interactions

  • Probing Protein–Nucleic Acid Interactions

  • Probing Protein–Ligand Interactions

  • Probing Amyloid Fibril Core

  • Conclusions

  • References