Resolution of Enantiomers via Biocatalysis

  1. Ernest L. Eliel2 and
  2. Samuel H. Wilen3
  1. Charles J. Sih and
  2. Shih-Hsiung Wu

Published Online: 26 FEB 2007

DOI: 10.1002/9780470147283.ch2

Topics in Stereochemistry, Volume 19

Topics in Stereochemistry, Volume 19

How to Cite

Sih, C. J. and Wu, S.-H. (1989) Resolution of Enantiomers via Biocatalysis, in Topics in Stereochemistry, Volume 19 (eds E. L. Eliel and S. H. Wilen), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470147283.ch2

Editor Information

  1. 2

    University of North Carolina, Chapel Hill, North Carolina

  2. 3

    City College, City University of New York, New York, New York

Author Information

  1. School of Pharmacy, University of Wisconsin, Madison, Wisconsin

Publication History

  1. Published Online: 26 FEB 2007
  2. Published Print: 1 JAN 1989

ISBN Information

Print ISBN: 9780471507529

Online ISBN: 9780470147283



  • kinetic control;
  • thermodynamic control;
  • enantioselectivity;
  • kinetic resolutions;
  • cyclic allylic alcohols


This chapter contains sections titled:

  • Introduction

  • General Mechanistic Principles

  • Strategies for Improving Enantioselectivity

  • Second-order Asymmetric Transformations

  • Selected Examples of Kinetic Resolutions

  • Conclusions