Stereochemistry of the Base-Promoted Michael Addition Reaction

  1. Ernest L. Eliel2 and
  2. Samuel H. Wilen3
  1. David A. Oare and
  2. Clayton H. Heathcock

Published Online: 26 FEB 2007

DOI: 10.1002/9780470147283.ch5

Topics in Stereochemistry, Volume 19

Topics in Stereochemistry, Volume 19

How to Cite

Oare, D. A. and Heathcock, C. H. (1989) Stereochemistry of the Base-Promoted Michael Addition Reaction, in Topics in Stereochemistry, Volume 19 (eds E. L. Eliel and S. H. Wilen), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470147283.ch5

Editor Information

  1. 2

    University of North Carolina, Chapel Hill, North Carolina

  2. 3

    City College, City University of New York, New York, New York

Author Information

  1. Department of Chemistry, University of California, Berkeley, California

Publication History

  1. Published Online: 26 FEB 2007
  2. Published Print: 1 JAN 1989

ISBN Information

Print ISBN: 9780471507529

Online ISBN: 9780470147283

SEARCH

Keywords:

  • driving force;
  • retro-michael addition;
  • diactivated acceptors;
  • ester amide enolates;
  • dithioester enethiolates

Summary

This chapter contains sections titled:

  • Introduction

  • Intermolecular Addition of Enolates to Various Michael Acceptors

  • Intramolecular Enolate Michael Additions

  • Sequential Michael Additions

  • Discussion of Models

  • Conclusions