7. Binding of Antibiotics to the Aminoacyl-Trna Site of Bacterial Ribosome

  1. Dev P. Arya
  1. Dale Kling1,
  2. Christine Chow2 and
  3. Shahriar Mobashery1

Published Online: 3 JAN 2007

DOI: 10.1002/9780470149676.ch7

Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery

Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery

How to Cite

Kling, D., Chow, C. and Mobashery, S. (2007) Binding of Antibiotics to the Aminoacyl-Trna Site of Bacterial Ribosome, in Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (ed D. P. Arya), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470149676.ch7

Editor Information

  1. Laboratory of Medicinal Chemistry, Department of Chemistry, Clemson University, Clemson, SC 29634, USA

Author Information

  1. 1

    Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA

  2. 2

    Department of Chemistry, Wayne State University, Detroit, MI 48202, USA

Publication History

  1. Published Online: 3 JAN 2007
  2. Published Print: 1 JUN 2007

ISBN Information

Print ISBN: 9780471743026

Online ISBN: 9780470149676

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Keywords:

  • antibiotic binding to aminoacyl-TRNA site;
  • minimum inhibitory concentrations (MICs);
  • aminoglycoside selectivity issue

Summary

This chapter contains sections titled:

  • Introduction

  • References