Chapter 11. Jump-Starting Tumor Immunity with Breast Cancer Therapeutics

  1. Rimas Orentas PhD2,
  2. James W. Hodge PhD3 and
  3. Bryon D. Johnson PhD4
  1. Leisha A. Emens MD, PhD

Published Online: 1 MAR 2007

DOI: 10.1002/9780470170113.ch11

Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity

How to Cite

Emens, L. A. (2007) Jump-Starting Tumor Immunity with Breast Cancer Therapeutics, in Cancer Vaccines and Tumor Immunity (eds R. Orentas, J. W. Hodge and B. D. Johnson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470170113.ch11

Editor Information

  1. 2

    Departments of Pediatrics, Medicine, Microbiology and Molecular Genetics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI, USA

  2. 3

    Department of Medical Biology, University of Tennessee Medical Center and Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

  3. 4

    Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin., Milwaukee, WI, USA

Author Information

  1. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Publication History

  1. Published Online: 1 MAR 2007
  2. Published Print: 22 JAN 2008

ISBN Information

Print ISBN: 9780470074749

Online ISBN: 9780470170113

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Keywords:

  • tumor immunity and cytoreduction;
  • breast cancer endocrine therapy - SERMS and SERDS;
  • breast cancer vaccines - improved clinical outcome

Summary

This chapter contains sections titled:

  • Introduction

  • Barriers to Effective Breast Tumor Immunity

  • Chemotherapy

  • Monoclonal Antibody and Endocrine Therapy for Breast Cancer and Tumor Immunity

  • The neu Transgenic Mouse Model

  • The Future: Manipulating Immunologic Checkpoints with Novel Immune-Based Therapies

  • Summary and Conclusions

  • References