Chapter 15. Intratumor Generation of Vigorous Antitumor Immune Responses

  1. Rimas Orentas PhD3,
  2. James W. Hodge PhD4 and
  3. Bryon D. Johnson PhD5
  1. Ping Yu MD1 and
  2. Yang-Xin Fu MD, PhD2

Published Online: 1 MAR 2007

DOI: 10.1002/9780470170113.ch15

Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity

How to Cite

Yu, P. and Fu, Y.-X. (2008) Intratumor Generation of Vigorous Antitumor Immune Responses, in Cancer Vaccines and Tumor Immunity (eds R. Orentas, J. W. Hodge and B. D. Johnson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470170113.ch15

Editor Information

  1. 3

    Departments of Pediatrics, Medicine, Microbiology and Molecular Genetics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI, USA

  2. 4

    Department of Medical Biology, University of Tennessee Medical Center and Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

  3. 5

    Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin., Milwaukee, WI, USA

Author Information

  1. 1

    Section of Dermatology, Department of Medicine, University of Chicago, Chicago, IL, USA

  2. 2

    Department of Pathology, Committee for Immunology, Committee for Molecular Pathogenesis and Molecular Medicine, University of Chicago, Chicago, IL, USA

Publication History

  1. Published Online: 1 MAR 2007
  2. Published Print: 22 JAN 2008

ISBN Information

Print ISBN: 9780470074749

Online ISBN: 9780470170113

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Keywords:

  • tumor-specific T cell priming;
  • active immunization and adoptive T cell transfer therapy;
  • antitumor effectors versus suppressors

Summary

This chapter contains sections titled:

  • Introduction

  • Priming of Tumor-Specific T Cells

  • Current Strategies for Cancer Immunotherapy

  • The Lesson from Autoimmunity

  • The Internal Tumor Environment

  • Conclusions

  • References