Chapter 18. Immune Evaluation of Cancer Vaccines

  1. Rimas Orentas PhD3,
  2. James W. Hodge PhD4 and
  3. Bryon D. Johnson PhD5
  1. Theresa L. Whiteside PhD Director1,2

Published Online: 1 MAR 2007

DOI: 10.1002/9780470170113.ch18

Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity

How to Cite

Whiteside, T. L. (2008) Immune Evaluation of Cancer Vaccines, in Cancer Vaccines and Tumor Immunity (eds R. Orentas, J. W. Hodge and B. D. Johnson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470170113.ch18

Editor Information

  1. 3

    Departments of Pediatrics, Medicine, Microbiology and Molecular Genetics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI, USA

  2. 4

    Department of Medical Biology, University of Tennessee Medical Center and Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

  3. 5

    Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin., Milwaukee, WI, USA

Author Information

  1. 1

    Immunologic Monitoring and Cellular Products Laboratory (IMCPL), University of Pittsburgh Cancer Institute, USA

  2. 2

    Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

Publication History

  1. Published Online: 1 MAR 2007
  2. Published Print: 22 JAN 2008

ISBN Information

Print ISBN: 9780470074749

Online ISBN: 9780470170113

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Keywords:

  • cancer vaccines - immune evaluation;
  • ELISpot or CFC assay;
  • QA/QC program in cancer vaccine evaluation

Summary

This chapter contains sections titled:

  • Introduction

  • Tools Necessary for Support of Vaccination Therapies

  • Objectives of Therapeutic Cancer Vaccines

  • Evaluation of Immune Competence Prior to Vaccination

  • Selection of Assays for Monitoring of Cancer Vaccines

  • The QA/QC Program and Assay Quality

  • Summary and Conclusions

  • References