Chapter 2. Fully Synthetic Carboyhydrate-Based Antitumor Vaccines

  1. Rimas Orentas PhD3,
  2. James W. Hodge PhD4 and
  3. Bryon D. Johnson PhD5
  1. Rebecca M. Wilson PhD1 and
  2. Samuel J. Danishefsky PhD Kettering Chair Director2

Published Online: 1 MAR 2007

DOI: 10.1002/9780470170113.ch2

Cancer Vaccines and Tumor Immunity

Cancer Vaccines and Tumor Immunity

How to Cite

Wilson, R. M. and Danishefsky, S. J. (2007) Fully Synthetic Carboyhydrate-Based Antitumor Vaccines, in Cancer Vaccines and Tumor Immunity (eds R. Orentas, J. W. Hodge and B. D. Johnson), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470170113.ch2

Editor Information

  1. 3

    Departments of Pediatrics, Medicine, Microbiology and Molecular Genetics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin, Milwaukee, WI, USA

  2. 4

    Department of Medical Biology, University of Tennessee Medical Center and Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

  3. 5

    Department of Pediatrics, Medical College of Wisconsin and the Children's Research Institute, Children's Hospital of Wisconsin., Milwaukee, WI, USA

Author Information

  1. 1

    Bioorganic Chemistry Laboratory, Memorial Sloan-Kettering Cancer Center, Columbia University, New York, NY, USA

  2. 2

    Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute, and Professor of Chemistry, Columbia University, New York, NY, USA

Publication History

  1. Published Online: 1 MAR 2007
  2. Published Print: 22 JAN 2008

ISBN Information

Print ISBN: 9780470074749

Online ISBN: 9780470170113

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Keywords:

  • synthetic carboyhydrate-based antitumor vaccines;
  • unimolecular multivalent vaccines;
  • unimolecular polyvalency and tumor markers

Summary

This chapter contains sections titled:

  • Introduction

  • Carbohydrate Synthesis

  • Synthetic Carbohydrate-Based Vaccines

  • Future Directions

  • References