13. The Bioactivity of PDMS-CaO-SiO2 Based Hybrid Materials Prepared by the Addition of Transition Metal Alkoxides

  1. Mineo Mizuno
  1. Manabu Fukushima1,
  2. Eiichi Yasuda1,
  3. Hideki Kita2,
  4. Masao Shimizu1,
  5. Yasuto Hoshkawa1 and
  6. Yasuhiro Tanabe1

Published Online: 27 MAR 2008

DOI: 10.1002/9780470291269.ch13

Advances in Bioceramics and Biocomposites: Ceramic Engineering and Science Proceedings, Volume 26, Number 6

Advances in Bioceramics and Biocomposites: Ceramic Engineering and Science Proceedings, Volume 26, Number 6

How to Cite

Fukushima, M., Yasuda, E., Kita, H., Shimizu, M., Hoshkawa, Y. and Tanabe, Y. (2005) The Bioactivity of PDMS-CaO-SiO2 Based Hybrid Materials Prepared by the Addition of Transition Metal Alkoxides, in Advances in Bioceramics and Biocomposites: Ceramic Engineering and Science Proceedings, Volume 26, Number 6 (ed M. Mizuno), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470291269.ch13

Author Information

  1. 1

    Materials & Structures Laboratory, Tokyo Institute of Technology, 4259, Nagatsuta, Midori-ku, Yokohama, Japan, 226–8503, Japan

  2. 2

    National Institute of Advanced Industrial Science and Technology, 2266–98 Shimo-Shidami, Moriyama-ku, Nagoya, Aichi 463–8560, Japan

Publication History

  1. Published Online: 27 MAR 2008
  2. Published Print: 1 JAN 2005

ISBN Information

Print ISBN: 9781574982367

Online ISBN: 9780470291269

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Keywords:

  • magnetic;
  • inorganic;
  • magnetic;
  • hydroxyl;
  • alkoxide

Summary

The bioactivity of organic inorganic hybrid materials derived from polydimethylsiloxane, tetraethoxysilane, calcium nitrate tetrahydrate and a different amount of pentaethoxy-niobium/tantalum was examined. We investigated the relationship between the hydroxyapatite depositions on the hybrid's surface in a simulated body fluid (KOKUBO solution) and the molecular structure oh hybrids. The in vitro formation of hydroxyapatite was characterized by using a simulated body fluid and the molecular structure of the hybrid was characterized by fourier transformed infrared and silicon 29 solid-state magic angle spinning nuclear magnetic resonance. The addition of a different amount of transition metal alkoxides lead to a different amount of silanol in the obtained hybrid materials. Additionally, the releasing ability of calcium from hybrid into simulated body fluid was different among the obtained hybrid materials, corresponding to the amount of transition metal. The hybrid material with a ratio of 0/1 and 1/0=Nb/Ta, polydimemylsiloxane/tetraemoxysilane=0. 1/1 and 0. 1=(Ta+Nb)/tetraethoxysilane showed the higher apatite formation ability.