Chapter 84. TEM–EDX Study of Process of Apatite Formation on Bioactive Ti–6A1–4V Alloy in Simulated Body Fluid

  1. Hau-Tay Lin and
  2. Mrityunjay Singh
  1. Hiroaki Takadama1,
  2. Mineo Mizuno1,
  3. Hyun-Min Kim2,
  4. Tadashi Kokubo2 and
  5. Takashi Nakamura3

Published Online: 26 MAR 2008

DOI: 10.1002/9780470294758.ch84

26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4

26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4

How to Cite

Takadama, H., Mizuno, M., Kim, H.-M., Kokubo, T. and Nakamura, T. (2008) TEM–EDX Study of Process of Apatite Formation on Bioactive Ti–6A1–4V Alloy in Simulated Body Fluid, in 26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4 (eds H.-T. Lin and M. Singh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470294758.ch84

Author Information

  1. 1

    Japan Fine Ceramics Center 2–4–1 Mutsuno, Atsuta-ku, Nagoya, 456–8587, Japan

  2. 2

    Graduate School of Engineering, Kyoto University Yoshida-honmachi, Sakyo-ku, Kyoto, 606–8501, Japan

  3. 3

    Graduate School of Medicine, Kyoto University Shogoin, Sakyo-ku, Kyoto, 606–8507, Japan

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 1 JAN 2002

ISBN Information

Print ISBN: 9780470375792

Online ISBN: 9780470294758

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Keywords:

  • apatite formation;
  • simulated body fluid;
  • bioactive alloy;
  • heat treatments;
  • transmission electron microscope

Summary

Bioactive Ti–6A1–4V alloy, prepared by NaOH and heat treatments, forms a bonelike apatite layer on its surface in the body, and bonds to bone through this apatite layer. In this study, the process of apatite formation on the alloy in a simulated body fluid (SBF) was investigated by transmission electron microscope. It was found that the Ti–OH groups formed on the alloy via exchange of Na+ ions with H3O+ ions, induce apatite formation indirectly by forming an amorphous calcium titanate and an amorphous calcium phosphate. The formation of the calcium titanate and calcium phosphate are proposed to be the results of electrostatic interactions between the Ti–OH groups and the calcium and phosphate ions in SBF.