Chapter 93. 3D CT Analyses of Porous Structures of Apatite Ceramics and in-Vivo Bone Formation

  1. Hau-Tay Lin and
  2. Mrityunjay Singh
  1. Y. Lkeda1,
  2. Y. Mizuta1,
  3. M. Mizuno1,
  4. K. Ohsawa2,
  5. M. Neo2 and
  6. T. Nakamura2

Published Online: 26 MAR 2008

DOI: 10.1002/9780470294758.ch93

26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4

26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4

How to Cite

Lkeda, Y., Mizuta, Y., Mizuno, M., Ohsawa, K., Neo, M. and Nakamura, T. (2002) 3D CT Analyses of Porous Structures of Apatite Ceramics and in-Vivo Bone Formation, in 26th Annual Conference on Composites, Advanced Ceramics, Materials, and Structures: B: Ceramic Engineering and Science Proceedings, Volume 23, Issue 4 (eds H.-T. Lin and M. Singh), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470294758.ch93

Author Information

  1. 1

    Japan Fine Ceramics Center 2–4–1, Mutsuno, Atsuta-ku, Nagoya, 456–8587 (Japan)

  2. 2

    K yoto University, Graduate School of Medicine 54, Shogoinkawaramati, Sakyo-ku, Kyoto, 606–8507 (Japan)

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 1 JAN 2002

ISBN Information

Print ISBN: 9780470375792

Online ISBN: 9780470294758

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Keywords:

  • ceramic baiomaterials;
  • apatite ceramics;
  • bone formation;
  • wollastonite glass;
  • hydroxyapatite

Summary

To evaluate bone formation on porous ceramic baiomaterials, such as hydroxy– apatite (HA) and apatite-wollastonite glass ceramic (AW–GC), a micro-focus X–ray CT method was employed to image and recostruct the 3–dimensional (3–D) structures of the ceramic specimens. The 100 CT cross section images of the specimens, composed of 512 × 512 pixels, formed one solid 3–D CT image of the specimen. The 3–D porous structures of the ceramics were analyzed by usig a bone-analyzing software, which gave the distribution of pore sizes and path sizes between pores for various specimens with different porosities. Some ceramic specimens soaked in simulated body fluid and those implanted in rat for in-vivo tests were investigated. After a few weeks in-vivo experiments, bone formation could be clearly observed and the amount of the formation could be estimated by the CT images.