Chapter 19. Iron: A Major Disease Modifier in Thalassemia

  1. M. N. V. Prasad
  1. Sujata Sinha

Published Online: 28 AUG 2008

DOI: 10.1002/9780470370124.ch19

Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health

Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health

How to Cite

Sinha, S. (2008) Iron: A Major Disease Modifier in Thalassemia, in Trace Elements as Contaminants and Nutrients: Consequences in Ecosystems and Human Health (ed M. N. V. Prasad), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470370124.ch19

Editor Information

  1. Department of Plant Sciences, University of Hyderabad, Hyderabad 500 046, India

Author Information

  1. BPS LAB-Centre for Diagnostic Hematology, Sankatmochan, Varanasi-221005 (UP), India

Publication History

  1. Published Online: 28 AUG 2008
  2. Published Print: 25 JUL 2008

ISBN Information

Print ISBN: 9780470180952

Online ISBN: 9780470370124

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Keywords:

  • iron disease modifier in thalassemia;
  • transferrin receptor regulation and expression;
  • heme synthesis role in erythropoiesis regulation

Summary

This chapter contains sections titled:

  • Introduction

  • Iron Metabolism: Current Concepts and Alterations in Thalassemia

  • Heme Synthesis and Its Role in Regulation of Erythropoiesis

  • Effect of Transfusional Iron Overload on Iron Homeostasis and Morbidity and Mortality

  • Evaluation and Management of Iron Overload

  • Summary

  • References