Chapter 1. Basic Mitochondrial Physiology in Cell Viability and Death

  1. James A. Dykens2,
  2. Yvonne Will3
  1. Lech Wojtczak,
  2. Krzysztof Zabłocki

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch1

Book Title

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Additional Information

How to Cite

Wojtczak, L. and Zabłocki, K. (2008) Basic Mitochondrial Physiology in Cell Viability and Death, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch1

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. Nencki Institute of Experimental Biology, Warsaw, Poland

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • mitochondrial physiology in cell viability and death;
  • mitochondrial ATP synthesis and oxidative phosphorylation;
  • calcium signaling and cellular calcium homeostasis

Summary

This chapter contains sections titled:

  • Introduction

  • Oxidative phosphorylation

  • Production of reactive oxygen species

  • Calcium signaling

  • Mitochondria and cell death

  • Concluding remarks: mitochondria as a pharmacological target

  • References

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