Chapter 13. Use of Oxygen-Sensitive Fluorescent Probes for the Assessment of Mitochondrial Function

  1. James A. Dykens3,
  2. Yvonne Will4
  1. James Hynes1,
  2. Tom´s C. O'Riordan1,
  3. Dmitri B. Papkovsky2

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch13

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

How to Cite

Hynes, J., O'Riordan, T. C. and Papkovsky, D. B. (2008) Use of Oxygen-Sensitive Fluorescent Probes for the Assessment of Mitochondrial Function, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch13

Editor Information

  1. 3

    Pfizer, Inc., Sandwich, UK

  2. 4

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. 1

    Luxcel Biosciences Ltd., BioInnovation Centre, University College–Cork, Cork, Ireland

  2. 2

    Biochemistry Department, University College–Cork, Cork, Ireland

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • oxygen-sensitive fluorescent probes;
  • quenched-fluorescence oxygen sensing;
  • fluorescence-based measurement approach and mitochondrial function

Summary

This chapter contains sections titled:

  • Introduction

  • Quenched-fluorescence oxygen sensing

  • Applications of oxygen-sensing probes

  • Conclusions and future perspectives

  • References