Chapter 14. Mitochondrial Dysfunction Assessed Quantitatively in Real Time by Measuring the Extracellular Flux of Oxygen and Protons

  1. James A. Dykens2,
  2. Yvonne Will3
  1. David Ferrick,
  2. Min Wu,
  3. Amy Swift,
  4. Andy Neilson

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch14

Book Title

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Additional Information

How to Cite

Ferrick, D., Wu, M., Swift, A. and Neilson, A. (2008) Mitochondrial Dysfunction Assessed Quantitatively in Real Time by Measuring the Extracellular Flux of Oxygen and Protons, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch14

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. Seahorse Bioscience, Billerica, Massachusetts, USA

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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CHAPTER TOOLS

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Keywords:

  • living cells and mitochondrial assessment;
  • mitochondrial function and cellular bioenergetic assessment;
  • glycolysis mitochondrial function changes

Summary

This chapter contains sections titled:

  • Introduction

  • The XF24 analyzer

  • Assessing mitochondrial function and cellular bioenergetics

  • Conclusions

  • References

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