Chapter 16. OXPHOS Complex Activity Assays and Dipstick Immunoassays for Assessment of OXPHOS Protein Levels

  1. James A. Dykens2,
  2. Yvonne Will3
  1. Sashi Nadanaciva

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch16

Book Title

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Additional Information

How to Cite

Nadanaciva, S. (2008) OXPHOS Complex Activity Assays and Dipstick Immunoassays for Assessment of OXPHOS Protein Levels, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch16

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. MitoSciences Inc., Eugene, Oregon; currently at Pfizer, Groton, Connecticut, USA

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

SEARCH

CHAPTER TOOLS

Get PDF (894K)

Keywords:

  • OXPHOS complex activity assays and dipstick immunoassays;
  • immunocapture-based OXPHOS activity assay specificity;
  • lateral flow dipstick immunoassay

Summary

This chapter contains sections titled:

  • Introduction

  • Immunocapture-based OXPHOS activity assays

  • Specificity of the immunocapture-based OXPHOS activity assays: effect of classical inhibitors

  • Screening of therapeutic drugs using the immunocapture-based OXPHOS activity assays

  • Lateral flow dipstick immunoassays

  • Future perspectives

  • References

Get PDF (894K)