Chapter 21. Clinical Assessment of Mitochondrial Function via [13C]Methionine Exhalation

  1. James A. Dykens2,
  2. Yvonne Will3
  1. Laura Milazzo

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch21

Book Title

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Additional Information

How to Cite

Milazzo, L. (2008) Clinical Assessment of Mitochondrial Function via [13C]Methionine Exhalation, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch21

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. Institute of Infectious and Tropical Diseases, University of Milan, L. Sacco Hospital, Milan, Italy

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • mitochondrial function - clinical assessment;
  • methionine breath test in liver mitochondrial toxicity;
  • HAART and HIV infection prognosis

Summary

This chapter contains sections titled:

  • Introduction

  • Development of exhalation assays

  • Methionine breath test

  • [13C]Methionine breath test in the study of drug-induced mitochondrial toxicity

  • Future perspectives

  • References

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