Chapter 6. Cardiovascular Toxicity of Mitochondrial Origin

  1. James A. Dykens3,
  2. Yvonne Will4
  1. Paulo J. Oliveira1,
  2. Vilma A. Sardão1,
  3. Kendall B. Wallace2

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch6

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

How to Cite

Oliveira, P. J., Sardão, V. A. and Wallace, K. B. (2008) Cardiovascular Toxicity of Mitochondrial Origin, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch6

Editor Information

  1. 3

    Pfizer, Inc., Sandwich, UK

  2. 4

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. 1

    Center for Neurosciences and Cell Biology, Department of Zoology, University of Coimbra, Coimbra, Portugal

  2. 2

    Department of Biochemistry and Molecular Biology, University of Minnesota Medical School, Duluth, Minnesota, USA

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • cardiovascular toxicity of mitochondrial origin;
  • nucleoside reverse transcriptase inhibitor (NRTI)-induced cardiomyopathy;
  • mitochondria xenobiotic-induced organopathy targets

Summary

This chapter contains sections titled:

  • Introduction

  • Induction of cardiovascular mitochondrial toxicity by xenobiotics

  • Conclusions

  • References