Chapter 7. Skeletal Muscle and Mitochondrial Toxicity

  1. James A. Dykens2,
  2. Yvonne Will3
  1. Timothy E. Johnson

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch7

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

How to Cite

Johnson, T. E. (2008) Skeletal Muscle and Mitochondrial Toxicity, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch7

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. Department of Safety Assessment, Merck Research Laboratories, West Point, Pennsylvania, USA

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • skeletal muscle and mitochondrial toxicity;
  • xenobiotic-induced skeletal muscle myopathy;
  • NRTI-associated myopathy and mitochondrial impairment

Summary

This chapter contains sections titled:

  • Introduction

  • Drug- and other xenobiotic-induced skeletal muscle myopathy and rhabdomyolysis

  • Conclusions

  • References