Chapter 8. Manifestations of Drug Toxicity on Mitochondria in the Nervous System

  1. James A. Dykens2,
  2. Yvonne Will3
  1. Ian J. Reynolds

Published Online: 22 JAN 2008

DOI: 10.1002/9780470372531.ch8

Book Title

Drug-Induced Mitochondrial Dysfunction

Drug-Induced Mitochondrial Dysfunction

Additional Information

How to Cite

Reynolds, I. J. (2008) Manifestations of Drug Toxicity on Mitochondria in the Nervous System, in Drug-Induced Mitochondrial Dysfunction (eds J. A. Dykens and Y. Will), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470372531.ch8

Editor Information

  1. 2

    Pfizer, Inc., Sandwich, UK

  2. 3

    Pfizer, Inc., Groton, Connecticut, USA

Author Information

  1. Neuroscience Drug Discovery, Merck Research Laboratories, West Point, Pennsylvania, USA

Publication History

  1. Published Online: 22 JAN 2008
  2. Published Print: 14 SEP 2008

ISBN Information

Print ISBN: 9780470111314

Online ISBN: 9780470372531

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Keywords:

  • drug toxicity manifestation on mitochondria;
  • mitochondria and retinal drug toxicity;
  • neuronal injury and mitochondrial mechanisms

Summary

This chapter contains sections titled:

  • Introduction

  • Mitochondrial mechanisms of peripheral neuropathy

  • Mitochondria and retinal drug toxicity

  • Mitochondria and ototoxicity

  • Mitochondrial mechanisms of CNS injury

  • Conclusions

  • References

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