Chapter 1. What Goes Wrong in Cancer

  1. Arthur B. Pardee1,2 and
  2. Gary S. Stein3
  1. Arthur B. Pardee1,2,
  2. Gary S. Stein3 and
  3. Elizabeth A. Bronstein3

Published Online: 26 MAR 2008

DOI: 10.1002/9780470374252.ch1

The Biology and Treatment of Cancer: Understanding Cancer

The Biology and Treatment of Cancer: Understanding Cancer

How to Cite

Pardee, A. B., Stein, G. S. and Bronstein, E. A. (2008) What Goes Wrong in Cancer, in The Biology and Treatment of Cancer: Understanding Cancer (eds A. B. Pardee and G. S. Stein), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470374252.ch1

Editor Information

  1. 1

    Department of Biological Chemistry, Harvard University, Dana-Farber Cancer Institute, USA

  2. 2

    Harvard Medical School, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts, USA

  3. 3

    Department of Cell Biology, UMASS Memorial Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA

Author Information

  1. 1

    Department of Biological Chemistry, Harvard University, Dana-Farber Cancer Institute, USA

  2. 2

    Harvard Medical School, Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts, USA

  3. 3

    Department of Cell Biology, UMASS Memorial Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts, USA

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 19 DEC 2008

ISBN Information

Print ISBN: 9780470009581

Online ISBN: 9780470374252

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Keywords:

  • biology of cancer and cancer cell biology;
  • cancer - its more dramatic and central processes;
  • detection of excess or structurally altered cyclin E protein - controling cell growth during breast cancer progression

Summary

This chapter contains sections titled:

  • Introduction

  • The Disease

  • Genes, Mutations, and Cancer

  • Cancer Cell Biology

  • Basic Cancer Research

  • Cancer Molecular Biology and Biochemistry

  • Chemotherapy

  • Earlier Detection

  • Summary

  • Detailed Reviews of Material in this Chapter

  • Sources of Further Information