7. Evidence-Based Medicine

  1. Gerald van Belle

Published Online: 26 SEP 2008

DOI: 10.1002/9780470377963.ch7

Statistical Rules of Thumb, Second Edition

Statistical Rules of Thumb, Second Edition

How to Cite

van Belle, G. (2008) Evidence-Based Medicine, in Statistical Rules of Thumb, Second Edition, John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470377963.ch7

Author Information

  1. University of Washington, Department of Biostatistics and Department of Environmental and Occupational Health Sciences, Seattle, WA

Publication History

  1. Published Online: 26 SEP 2008
  2. Published Print: 18 AUG 2008

ISBN Information

Print ISBN: 9780470144480

Online ISBN: 9780470377963

SEARCH

Keywords:

  • evidence-based medicine (EBM);
  • POEM;
  • DOE;
  • NNT;
  • randomized clinical trial (RCT)

Summary

This chapter contains sections titled:

  • Strength of Evidence

  • Relevance of Information: POEM vs. DOE

  • Begin with Absolute Risk Reduction, then Follow with Relative Risk

  • The Number Needed to Treat (NNT) is Clinically Useful

  • Variability in Response to Treatment Needs to be Considered

  • Safety is the Weak Component of EBM

  • Intent to Treat is the Default Analysis

  • Use Prior Information but not Priors

  • The Four Key Questions for Meta-analysts