Chapter 7. Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways, Potential Targets, and Noise

  1. Anton Yuryev PhD
  1. John Farley MD Associate Professor1,
  2. Laurent L. Ozbun PhD2 and
  3. Michael J. Birrer MD, PhD2

Published Online: 21 APR 2008

DOI: 10.1002/9780470399279.ch7

Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications

Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications

How to Cite

Farley, J., Ozbun, L. L. and Birrer, M. J. (2008) Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways, Potential Targets, and Noise, in Pathway Analysis for Drug Discovery: Computational Infrastructure and Applications (ed A. Yuryev), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470399279.ch7

Editor Information

  1. Ariadne Genomics Inc., 9430 Key West Avenue, Suite 113, Rockville, MD 20850, USA

Author Information

  1. 1

    Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA

  2. 2

    Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Bldg 37, Room 1130, Bethesda, MD 20892, USA

Publication History

  1. Published Online: 21 APR 2008
  2. Published Print: 12 SEP 2008

Book Series:

  1. Wiley Series on Technologies for the Pharmaceutical Industry

Book Series Editors:

  1. Sean Ekins

ISBN Information

Print ISBN: 9780470107058

Online ISBN: 9780470399279

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Keywords:

  • whole-genome expression profiling;
  • biologic relationship among ovarian cancers;
  • pathway analysis tool in signaling network identification

Summary

This chapter contains sections titled:

  • Introduction

  • Expression Profiling of Ovarian Cancer

  • Defining the Biologic Relationship among Ovarian Tumors of Varying Grade

  • Defining the Biologic Relationship among Ovarian Cancers of Different Histologies

  • Complexities of Whole-Genome Profiling

  • In Silico Pathway Identification

  • Noise

  • References