Chapter 3. Nuclear Receptor-Mediated Regulation of Phase II Conjugating Enzymes
- Wen Xie2,3
Published Online: 14 MAY 2008
DOI: 10.1002/9780470409107.ch3
Copyright © 2009 John Wiley & Sons, Inc.
Book Title
Nuclear Receptors in Drug Metabolism
Additional Information
How to Cite
Barbier, O. (2008) Nuclear Receptor-Mediated Regulation of Phase II Conjugating Enzymes, in Nuclear Receptors in Drug Metabolism (ed W. Xie), John Wiley & Sons, Inc., Hoboken, NJ, USA. doi: 10.1002/9780470409107.ch3
Editor Information
- 2
Center for Pharmacogenetics, University of Pittsburgh, Pittsburgh, PA, USA
- 3
Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USA
Publication History
- Published Online: 14 MAY 2008
- Published Print: 24 OCT 2008
ISBN Information
Print ISBN: 9780470086797
Online ISBN: 9780470409107
- Summary
- Chapter
- References
Keywords:
- phase I nuclear receptor-mediated regulation;
- CAR and PXR xenosensors;
- PPARs and PHASE II XMEs regulation
Summary
This chapter contains sections titled:
Introduction
Phase II Drug Metabolizing Enzymes
The Xenosensors CAR and PXR: Two Master Regulators of Phase II Metabolism
AhR and Nrf2, Two Important Regulators of Phase II Enzymes
PPARs and Phase II XMEs Regulation
FXR/LXRα and Phase II XMEs Regulation
HNF and Phase II XMEs Regulation
Regulation of Phase II Conjugating Enzymes by Steroid and Thyroid Receptors
Concluding Remarks and Perspectives
References